US drugmaker Merck scraps £1bn London research centre and cuts 125 science jobs New blow to UK’s key life science sector as industry body says country is losing ground on investment and research
Rachel Reeves tells private equity bosses she plans to shut down more regulators Chancellor stopped short of saying which regulators were in government’s crosshairs
Starmer tightens grip on economic policy by strengthening autumn ‘budget board’ Key figures from No 10 and No 11 appointed to group include Torsten Bell, new economic adviser Minouche Shafik and comms chief Tim Allan
CBI boss calls for Reeves to tear up Labour’s pledge not to raise tax Rain Newton-Smith tells chancellor ‘the time for tinkering is over’ and revisit promise not to raise taxes on working people
Peter Kyle, the ‘tech bro’ minister charged with kickstarting UK growth ‘Hard-working’ business secretary opens his tenure with delicate trade missions to Washington and Beijing
Reform UK would axe any high-speed northern rail schemes, says Richard Tice Deputy leader tells firms considering bidding for contracts to ‘not bother’ as party would spend on what ‘country needs more’
I’m not running for Labour deputy leader. I want the freedom to fight for an economic reset The failed status quo and the OBR are holding us back from investing in ways that will transform the UK for the better, says Labour MP Louise Haigh
UK politics: Creasy leaves open chance of Labour deputy leadership bid and calls for Palestine Action law change – as it happened The MP said police should be focusing on people who are members of the group, not those who ‘recklessly express support’ for it
George Osborne ‘to miss out on big windfall’ from sale of investment bank Former chancellor is now partner at Robey Warshaw but is expected to move to part-time role, report says
New business secretary Peter Kyle going to China for trade talks this week Former science secretary promoted in reshuffle to continue UK efforts to revitalise trade relationship with Beijing
Lord Paul obituary Industrialist and philanthropist who served as deputy speaker of the House of Lords for two years
London tube users warned to plan for disruption as strike action escalates Action will bring services to early finish on Sunday and close underground entirely for four days from Monday
Unite’s Sharon Graham: ‘Labour has one year to get it right. Farage is on their tail’ As workers feel the pressure and more people tune in to Reform, Starmer risks losing union members’ support, Graham says
Reeves’s £50bn problem solved: stop splashing it in pension tax relief Older people would save anyway if state support was more limited, and overhaul of council tax would net billions more
An ale star cast: pint-pulling Rupert Everett surprises country pub’s punters Hollywood actor helps out at the Swan at Enford in Wiltshire as he and his neighbours fight to save their local